PPAR-γ agonists, mainly 15d-PGJ2, reduce eosinophil recruitment following allergen challenge
نویسندگان
چکیده
منابع مشابه
15-Deoxy-Δ12,14-Prostaglandin J2 Protects PC12 cells from LPS-Induced Cell Death Through Nrf2 pathway in PPAR-γ Dependent Manner
Introduction: The inflammatory response requires a coordinated integration of various signaling pathway including cyclooxygenase (COX). COX catalyzes the formation of prostaglandins from arachidonic acid. Among prostaglandins, 15-Deoxy-D12, 14-prostaglandin J2 (15d-PGJ2), an endogenous ligand of Peroxisome proliferator-activated receptor-gamma (PPAR-γ), has been demonstrated to have anti-inflam...
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ژورنال
عنوان ژورنال: Cellular Immunology
سال: 2012
ISSN: 0008-8749
DOI: 10.1016/j.cellimm.2011.11.010